Frailty and Metabolic Syndrome cast gaunt (and flabby) shadows over our aging world; the need for new therapeutics has never been so urgent. Follistatin gene therapy addresses two pressing epidemics: frailty from sarcopenia (age-related muscle loss) and Metabolic Syndrome — a constellation of issues including insulin insensitivity, hypertension, high cholesterol…

Klotho is named after one of the three Fates from Greek mythology. She spins the thread of life. Appropriately, this protein is pivotal to the aging process. Aging’s causes are manifold, but some, like sinking Klotho levels, are low-hanging fruit for regenerative modalities like gene therapy. Makoto Kuro-o discovered Klotho…

Have you ever wondered if there is a way to stop aging? What can advances in anti-aging research do for you today? Are you interested in living a longer, healthier life? Then the Buying Time Podcast is for you! Hosted by Liz Parrish, CEO of BioViva Science, and Saravanan Balakrishnan…

Aging is a complex process, a river fed by several tributaries connected by countless interweaving streams. Its direction is set inexorably towards infirmity, or so it would first appear. Daunting as navigation may seem, their interrelatedness should inspire hope instead of fear. Aging is undeniably the root of the most…

Why do we age? All adaptations should improve an organism’s chance of producing viable offspring. Shouldn’t they? If this was true, species with abnormally long reproductive windows should rule across kingdoms and clades. This simplistic interpretation of natural selection would guarantee increasingly lengthy lifespans for all. …

Of the three great Stoics, Seneca always interested me the least. A playwright and professional philosopher, he seemed unlikely to be acquainted with the more mundane forms of suffering that beset humanity. This made him seem unfit to propound upon a philosophy concerned with right conduct under challenging circumstances. Marcus…

Space is not a hospitable place. Radiation, zero gravity, and the vast distances between stops make interstellar travel look like a pipe dream right now, but they can be made more manageable with gene therapy. Along with obvious choices like follistatin to fight the loss of muscle mass, anti-aging gene…

Dementia is closely linked to the aging process. It robs people of their cognitive functioning, memories and, ultimately, their very sense of self. Countless studies have been conducted to get to the bottom of things. One finding has come up again and again: telomere attrition is directly implicated with the…

While it has long been observed that people tend to age at different rates, the underlying mechanisms were not always understood. Conventional wisdom is partly correct to attribute this phenomenon to genetics. Someone who ages gracefully and enjoys a lengthy life is thought to have “good genes.” …